Laboratory Diagnostics of Opportunistic Infections and Monitoring of HIV Treatment Quality

Training Materials: 
Course description

Course name Laboratory Diagnostics for Opportunistic Infections (OIs) and Monitoring of HIV Treatment Quality
Main Learning Objectives
  • Study spectrum and incidence of opportunistic infections in HIV-infected patients
  •  Study significance of standard instrument examination methods (X-ray, computerized tomography, MRI, ultrasound and bronchoscopies) to detect the etiology of secondary organ system complications
  • Study clinical significance of molecular diagnostic methods for establishing the etiology of organ system complications
  • Study procedures for examination and etiological analysis of organ system complications in patients with late-stage HIV infection
  • Learn about the implementation of clinical monitoring of treatment quality for HIV patients
  • Study issues of immunological failure of ART
  • Study issues of virological failure of ART
  • Study the development of drug resistance to ARV medications
  • Study the significance of certain mutations in the development of drug resistance
  • Learn about methods of detecting viral drug resistance
  • Study the clinical significance and procedures of genotyping
  • Learn about indications for examination for viral drug resistance to ARV medications under limited-resource conditions
  • Learn to apply the knowledge gained in practical settings
Key Topics  Laboratory diagnostics for OIs in HIV-infected patients; clinical significance of standard instrument examination methods and molecular diagnostics for detecting the etiology of secondary organ system complications in HIVinfected patients; OI examination procedures; monitoring efficacy of ART; immunological and virological failure of ART; development of drug resistance to ARVs; methods of detecting drug resistance and indications for testing; clinical significance of certain mutations
Basis of Curriculum, Key Teaching Documents and Materials provided
  • HIV/AIDS Treatment and Care Clinical Protocols for the WHO European Region (2006)
  • Relevant national protocols and policies
  • Medical Management of HIV Infection, J. Bartlett, J. Gallant, 2007
  • Clinical Care Options (www.clinicaloptions.com)
  • Set of slides and handouts.
  • Lectures and clinical case studies prepared by Russian and international experts
All materials available printed or electronically
Teaching Methods Lectures, small group instruction, clinical case studies, and bedside training.
Target Audience Physicians specializing in infectious diseases and specialists in related disciplines who treat HIV-infected patients.
Maximum class size: 18-24 participants
Faculty National and international instructors with expertise in treating HIV infection.
Duration two-three-day course, including theoretical and practical sessions; training is conducted at healthcare facilities that specialize in treating HIV infection.